While the scientific community has made huge advances in understanding the epidemiology and clinical aspects of COVID-19, there is still more critical research needed, particularly in the areas of vaccine and drug development. High-quality flow cytometry analysis can provide powerful insights across various clinical areas of your SARS-CoV-2 research, and FlowMetric’s team is here to provide expert support to accelerate your research goals.
Immunophenotyping for the testing of re-purposed and candidate vaccines for SARS-CoV-2 in animal models and human clinical trials. Including the assessment of T-cell memory for enhanced vaccine development.
Cytokine profiling of COVID-19 patients and disease model systems.
Drug development and target-binding studies, including receptor binding and profiling of receptor expression on immune cells.
Characterization of anti-viral pathways, including the initial key mediators of the initial immune response to SARS-CoV-2 and their downstream signaling pathways towards interferon-mediated mechanisms.
Complex tSNE analysis of inflammatory profiling and changing T-cell, B-cell, NK, dendritic, myeloid, and monocyte profiling of patients. Providing critical insights into the role of innate and adapted immune responses to the virus.
Serological testing for SARS-CoV-2 exposure.
FlowMetric has over 10 years of experience in immunophenotyping and immune system monitoring using flow cytometry. Our team can support your research by designing and validating flow cytometry panels to analyze up to 20 parameters of immune responses. Critical experimental design, upfront, can ensure you get the most out of your clinical samples from measuring antigen-specific T-cell and B-cell responses, MHC-tetramers, to monitoring the establishment of T-cell memory.
The characterization of cytokine profiles in response to immunomodulators is central to understanding disease pathogenesis.
Flowmetric’s expertise in intracellular and released cytokine measurement can help profile and track T-plasticity within your clinical samples, as well as provide rapid patient stratification and help identify those most at risk of cytokine storm. Whether your research requires qualitative or quantitative read-outs, FlowMetric can provide fit-for-purpose solutions for cytokine detection and measurement.
FlowMetric’s scientists are experts in humoral and cell-mediated immune response and have the ability to measure up to 40 parameters simultaneously, which provides significant value-add to your SARS-CoV-2 research initiatives.